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【公司名稱】 廣州健侖生物科技有限公司
【市場(chǎng)部】    楊永漢

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【騰訊  】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103室

這項(xiàng)發(fā)現(xiàn)進(jìn)一步闡明了人類記憶的神經(jīng)基礎(chǔ)，zui終可能提供有關(guān)某些疾病和影響記憶的身體狀況，例如阿耳滋海默氏病(老年癡呆癥)和癲癇癥，新療法的新見解。“為了真正了解大腦是如何描繪記憶的，我們必須理解記憶是如何由大腦的基本計(jì)算單元——單個(gè)神經(jīng)元——以及它們所組成的神經(jīng)元網(wǎng)絡(luò)所體現(xiàn)的。”這項(xiàng)研究的高級(jí)作者、巴羅研究所神經(jīng)工程項(xiàng)目主任皮特·N·斯坦梅茨(Peter N Steinmetz)博士這樣說道。“了解記憶存儲(chǔ)和取回的機(jī)制是理解如何更好地治療影響老年群體的癡呆疾病的至關(guān)重要的一步。”
斯坦梅茨和這項(xiàng)研究的*作者、心理學(xué)杰出教授約翰·T·維史德(John T. Wixted)博士和神經(jīng)科學(xué)、精神病學(xué)和心理學(xué)學(xué)院教授拉里·R·斯奎爾(Larry R. Squire)博士以及他們的同事評(píng)估了9名癲癇癥病人，后者的大腦都被植入電極以檢測(cè)癲癇的發(fā)作，這項(xiàng)檢測(cè)將記錄單個(gè)神經(jīng)元水平的活動(dòng)。
病人被要求記住電腦屏幕上的一系列詞匯，然后觀測(cè)第二個(gè)、包含更多詞匯的更長(zhǎng)的詞匯名單。隨后他們被要求選出之前見到的詞匯，從而檢測(cè)他們記住這些詞匯的能力。看見*個(gè)名單上存在的詞匯時(shí)與看見那些不存在名單上的詞匯時(shí)所產(chǎn)生的細(xì)胞活動(dòng)存在差異，這暗示著海馬體細(xì)胞體現(xiàn)了病人對(duì)這些詞匯的記憶。

This finding further elucidates the neural basis of human memory and may eventually provide new insights into certain diseases and conditions affecting memory, such as Alzheimer's disease (Alzheimer's disease) and epilepsy, new therapies. "To really understand how the brain portrays memory, we have to understand how memory is represented by the brain's basic computational unit, a single neuron, and the network of neurons they make up." A senior author of the study, Peter N Steinmetz, PhD, neurological project director at the Barlow Institute, said. "Understanding the mechanisms for memory storage and retrieval is a crucial step in understanding how to better treat dementia affecting older people."
Steinmetz and lead author of the study, Ph.D. John T. Wixted, professor of psychology, and Larry R. Squire, professor of neuroscience, psychiatry and psychology Dr. R. Squire and their colleagues evaluated nine epilepsy patients whose brains were implanted with electrodes to detect epileptic seizures. This test will record the activity of individual neurons.
The patient is asked to memorize a series of words on the computer screen and then watch the second, longer list of words that contains more words. They were then asked to pick out the words they had seen before and test their ability to remember those words. Differences in cell activity from seeing the words on the first list when they see the words that do not exist on the list suggest that the cells in the hippocampus reflect the patient's memory of those words.