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Seracare心肌磷脂IgG(Cardiolipin IgG)

Seracare心肌磷脂IgG(Cardiolipin IgG)

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美國SeracareSeracare心肌磷脂IgG(Cardiolipin IgG) 陽性質(zhì)控品對照品 需要了解更多Seracare產(chǎn)品可以咨詢我們,本產(chǎn)品由廣州健侖生物科技有限公司提供

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美國Seracare心肌磷脂IgG(Cardiolipin IgG)

廣州健侖生物科技有限公司

廣州健侖長期供應各種生物原料,主要代理品牌:美國Seracare、西班牙Certest、美國Fuller等等。

主要產(chǎn)品包括各種標準品、陽性對照品、單克隆抗原抗體。

其中常見的有:弓形蟲病、西尼羅河病毒、類風濕因子、瘧疾、麻疹、萊姆病、百日咳桿菌、大腸桿菌、鼠傷寒沙門氏菌、李斯特菌等陽性對照品。

美國Seracare心肌磷脂IgG(Cardiolipin IgG)

我司還提供其它進口或國產(chǎn)試劑盒:登革熱、瘧疾、流感、A鏈球菌、合胞病毒、腮病毒、乙腦、寨卡、黃熱病、基孔肯雅熱、克錐蟲病、違禁品濫用、肺炎球菌、軍團菌、化妝品檢測、食品安全檢測等試劑盒以及日本生研細菌分型診斷血清、德國SiFin診斷血清、丹麥SSI診斷血清等產(chǎn)品。

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【Seracare產(chǎn)品介紹】

編號

英文名稱

中文名稱

JL-FA-01

Amebiasis (AME)

阿米巴病

JL-FA-02

Allergens, Rast scores

過敏原,放射性過敏原吸收實驗。指對特定的人群引起免疫反應或者過敏反應的食品中的蛋白質(zhì)

JL-FA-03

Allergens, Rast scores negative

過敏原,放射性過敏原吸收實驗陰性

JL-FA-04

Anti-cyclic citrullinated peptide Antibody (CCP) Arthritis

抗環(huán)瓜氨酸肽抗體

JL-FA-05

ASCA Saccharomyces Cerevi

人抗釀酒酵母抗體(ASCA)

JL-FA-06

Aspergillis

麴菌病

JL-FA-07

Beta 2 Glycoprotein

β2糖蛋白

JL-FA-08

Beta 2 Glycoprotein  IgM

β2糖蛋白 IGM

JL-FA-09

Bordela Pertussis

百日咳桿菌

JL-FA-10

Bordela Pertussis IgM

百日咳桿菌 IGM

JL-FA-11

C-ANCA

C-抗中性粒細胞胞漿抗體(ANCA)

JL-FA-12

Cardiolipin

心肌磷脂

JL-FA-13

Cardiolipin IgA

心肌磷脂 IGA

JL-FA-14

Cardiolipin IgG

心肌磷脂 IGG

JL-FA-15

Cardiolipin IgM

心肌磷脂 IGM

JL-FA-16

Cerebral Spinal Fluid

腦脊髓液

JL-FA-17

Chagas

恰加斯病/南美錐蟲

JL-FA-18

Chlamydia

衣原體

JL-FA-19

Chlamydia IgA

衣原體IGA

JL-FA-20

Chlamydia IgG

衣原體IGG

JL-FA-21

Chlamydia IgM

衣原體IGM

JL-FA-22

Chlamydia Neg

衣原體陰性

JL-FA-23

Clotting Factor C3

凝固因子C3

JL-FA-24

Clotting Factor C4

凝固因子C4

JL-FA-25

Coccidiodes

球孢菌

JL-FA-26

Cytomegalovirus (CMV) Neg

巨細胞病毒抗體陰性

JL-FA-27

CMV IgG

巨細胞病毒 IGG陽性

JL-FA-28

CMV IgM VCA

巨細胞病毒 IGM 陽性

JL-FA-29

C-Reactive Protein (CRP)

C-反應蛋白質(zhì)

JL-FA-30

Dengue Fever

登革熱

JL-FA-31

Dengue Fever IgM

登革熱 IGM

JL-FA-32

DS (Double Stranded) DNA

雙鏈脫氧核糖核酸

JL-FA-33

EBNA (Epstein-Barr nuclear antigen) IgG

EB病毒核抗原 IGG

JL-FA-34

EBNA (Epstein-Barr nuclear antigen) IgM

EB病毒核抗原 IGM

JL-FA-35

Epstein Barr Virus (EBV) Negative Plasma

EB病毒陰性血漿

JL-FA-36

Epstein Barr Virus (EBV) EA IgM

EB病毒早期抗原 IGM

JL-FA-37

Epstein Barr Virus (EBV) VCA IgM

EB病毒殼蛋白  IGM

JL-FA-38

Epstein Barr Virus (EBV) EA IgG

EB病毒早期抗原 IGG

JL-FA-39

EMA (Endomysial Antibodies)

肌內(nèi)膜

JL-FA-40

Gliadin

麩蛋白,麥醇溶蛋白,麥膠蛋白

JL-FA-41

Gliadin IgG

麥醇溶蛋白  IGG

JL-FA-42

Gliadin IgA

麥醇溶蛋白 IGA

JL-FA-43

Glomerular Basement Membrane (GBMA)

腎小球基底膜病

JL-FA-44

Helicobacter pylori IgA

幽門螺旋桿菌IGA

JL-FA-45

Helicobacter pylori IgG

幽門螺旋桿菌IGG

JL-FA-46

Helicobacter pylori IgM

幽門螺旋桿菌IGM

JL-FA-47

Helicobacter pylori Negative

幽門螺旋桿菌陰性

JL-FA-48

Helicobacter pylori Positive Plasma

幽門螺旋桿菌陰性血漿

JL-FA-49

Hepatitis A Virus (HAV) Pos. Plasma

甲型肝炎病毒陽性血漿

JL-FA-50

Hepatitis A Virus (HAV) IgM

甲型肝炎病毒IGM

JL-FA-51

Hepatitis B Core (HBc) IgG

乙型肝炎病毒核心 IGG

JL-FA-52

Hepatitis B Core (HBc) IgM

乙型肝炎病毒核心 IGM

JL-FA-53

Anti Hbe (Antibody to HBV antigen)

乙肝抗體

JL-FA-54

Hepatitis Delta Virus

丁型肝炎病毒

JL-FA-55

HBeAg (HBV e antigen)

乙肝 E抗原

JL-FA-56

anti-HBs (HBV surface antibody)

乙肝表面抗體

JL-FA-57

Hepatitis B (HBsAg) "Chronic"

乙型肝炎(乙肝表面抗原)“慢性病

JL-FA-58

HBsAg (HBV surface antigen) Serum

乙肝表面抗原血清

JL-FA-59

HBsAg (AD)

乙肝表面抗原(AD)

JL-FA-60

HBsAg (AY)

乙肝表面抗原(AY)

JL-FA-61

HBV Positive Plasma

乙肝陽性血漿

JL-FA-62

HBV DNA Plasma

乙肝DNA血漿

JL-FA-63

HBV DNA Serum

乙肝DNA血清

JL-FA-64

HBV DNA type A

 A型 乙肝DNA

JL-FA-65

HBV DNA type B

 B型 乙肝DNA

JL-FA-66

HBV DNA type C

 C型 乙肝DNA

JL-FA-67

HBV DNA type D

 D型 乙肝DNA

JL-FA-68

HBV DNA type E

 E型 乙肝DNA

JL-FA-69

HBV DNA type F

 F型 乙肝DNA

JL-FA-70

HBV Antibody HCV Antibody Plasma CO-INFECTED

乙肝和丙肝聯(lián)合感染血漿

JL-FA-71

HCV (Hepatitis C Virus) Antibody

丙型肝炎抗體

JL-FA-72

HCV Core Antigen Positive

丙肝核心抗原 陽性

JL-FA-73

HCV RNA PLASMA Genotype 1

基因1型丙肝RNA 血漿

JL-FA-74

HCV RNA PLASMA Genotype 2

基因2型丙肝RNA 血漿

JL-FA-75

HCV RNA PLASMA Genotype 3

基因3型丙肝RNA 血漿

JL-FA-76

HCV RNA PLASMA Genotype 4

基因4型丙肝RNA 血漿

JL-FA-77

HCV RNA PLASMA Genotype 5

基因5型丙肝RNA 血漿

JL-FA-78

HCV RNA PLASMA Genotype 6

基因6型丙肝RNA 血漿

JL-FA-79

HCV Riba single band

丙肝免疫印跡單波段

JL-FA-80

HCV RIBA Pos. (multiple bands)

丙肝免疫印跡陽性多波段

JL-FA-81

HCV Negative

丙肝陰性

JL-FA-82

HCV RNA Pos (quantitative)

丙肝RNA陽性(定量)

JL-FA-83

Hepatitis E

戊型肝炎

JL-FA-84

Herpes Simplex Virus (HSV)1/2 Positive Plasma

單純性皰疹病毒1/2陽性血漿

JL-FA-85

Herpes Simplex Virus (HSV) 1 Negative Plasma

單純性皰疹病毒1 陰性血漿

JL-FA-86

Herpes Simplex Virus (HSV) 1 IgG

單純性皰疹病毒1 IGG

JL-FA-87

Herpes Simplex Virus (HSV 1) IgM

單純性皰疹病毒1 IGM

JL-FA-88

Herpes Simplex Virus (HSV) 2 IgG

單純性皰疹病毒2 IGG

JL-FA-89

Herpes Simplex Virus (HSV) 2 IgM

單純性皰疹病毒2 IGG

JL-FA-90

Histone

組蛋白

JL-FA-91

Human Anti Mouse Ab (HAMA)

人抗鼠抗體

JL-FA-92

Human immunodeficiency virus (HIV) 1 Neg

HIV  I 陰性

JL-FA-93

anti Human immunodeficiency virus (HIV) 1 Plasma

抗HIV  I 血漿

JL-FA-94

anti Human immunodeficiency virus (HIV) 1 Serum

抗HIV  I 血清

JL-FA-95

anti Human immunodeficiency virus (HIV) 2 Western Blot Tested

抗HIV  2 免疫印跡

JL-FA-96

anti Human immunodeficiency virus (HIV) 1/2 2 HIV (+)

抗HIV 1/2 2  HIV陽性

JL-FA-97

Human immunodeficiency virus (HIV) Ag

HIV抗原

JL-FA-98

HIV RNA (quantitative) Plasma

HIV RNA 定量血漿

JL-FA-99

HIV RNA (quantitative) Serum

HIV RNA 定量血清

JL-FA-100

HIV1 Subtype A

HIV1  亞型A

JL-FA-101

HIV1 Subtype B

HIV1  亞型B

JL-FA-102

HIV1 Subtype C

HIV1  亞型C

JL-FA-103

HIV1 Subtype D

HIV1  亞型D

JL-FA-104

HIV1 Subtype E

HIV1  亞型E

JL-FA-105

HIV1 Subtype F

HIV1  亞型F

JL-FA-106

HIV1 Subtype G

HIV1  亞型G

JL-FA-107

HIV1 Subtype H

HIV1  亞型H

JL-FA-108

HIV1 Subtype J

HIV1  亞型J

JL-FA-109

HIV1 Subtype K

HIV1  亞型K

JL-FA-110

HIV1 Group O

HIV1  亞型O

JL-FA-111

Human immunodeficiency virus (HIV) 2 Antibody Plasma

HIV 2 抗體血漿

JL-FA-112

Human immunodeficiency virus (HIV) 2 Antibody Serum

HIV 2 抗體血清

JL-FA-113

HPV (Human Papiloma Virus) Negative

人乳狀瘤病毒HPV陰性

JL-FA-114

HPV (Human Papiloma Virus) Positive

人乳狀瘤病毒HPV陽性

JL-FA-115

Human immunodeficiency virus (HIV) Antibody HCV Antibody Plasma COINFECTED

HIV 抗體  HCV

JL-FA-116

Human T-cell Lymphotropic Virus (HTLV) I/II

人嗜T淋巴細胞病毒(HTLV) I/II

JL-FA-117

Human T-cell Lymphotropic Virus (HTLV) I

人嗜T淋巴細胞病毒(HTLV) I

JL-FA-118

Human T-cell Lymphotropic Virus (HTLV) II

人嗜T淋巴細胞病毒(HTLV) II

JL-FA-119

Jo-1

多發(fā)性肌炎抗原JO-1

JL-FA-120

IgE < 5,000 Ku/L

IgE < 5,000 Ku/L

JL-FA-121

Legionella

軍團桿菌屬

JL-FA-122

Leptospira

軍團桿菌屬

JL-FA-123

Lyme Disease

萊姆(氏)病:蜱傳播的全身性疾病,常在夏季發(fā)生

JL-FA-124

Lyme IgG

萊姆(氏)病 IGG

JL-FA-125

Lyme IgM

萊姆(氏)病 IGM

JL-FA-126

Lyme Disease Neg

萊姆(氏)病 陰性

JL-FA-127

Malaria

瘧疾

JL-FA-128

Mononucleosis (infectious)

單核細胞增多癥(有傳染性的)

JL-FA-129

Mononucleosis Negative

單核細胞增多癥陰性

JL-FA-130

Measles Negative

麻疹 陰性

JL-FA-131

Measles IgG

麻疹 IGG

JL-FA-132

Measles IgM

麻疹  IGM

JL-FA-133

Microsomal Anti-thyroid peroxidase antibody (TPO) Positive Plasma Standard Titer (typically 1,000-3,000 IU/mL)

微粒體抗甲狀腺過氧化物酶抗體

JL-FA-134

Microsomal Anti-thyroid peroxidase antibody (TPO) Negative Plasma

微粒體抗甲狀腺過氧化物酶抗體

JL-FA-135

Anti-mitochondrial antibody (AMA)

抗線粒體抗體

JL-FA-136

Multiple Sclerosis

多發(fā)性硬化癥

JL-FA-137

Mumps IgG

流行性腮腺炎 IGG

JL-FA-138

Mumps Ab IgM

流行性腮腺炎抗體 IGM

JL-FA-139

Mumps Antibody Negative Plasma

流行性腮腺炎抗體陰性血漿

JL-FA-140

Mumps Antibody Negative Serum

流行性腮腺炎抗體陰性血清

JL-FA-141

Myeloma Plasma

骨髓瘤血漿

JL-FA-142

Myeloma IgA

骨髓瘤IGA

JL-FA-143

Myeloma IgE

骨髓瘤IGE

JL-FA-144

Myeloma IgG

骨髓瘤IGG

JL-FA-145

Myeloma IgM

骨髓瘤IGM

JL-FA-146

Mycoplasma

支原體

JL-FA-147

Mycoplasma Negative

支原體陰性

JL-FA-148

Mycoplasma IgG

支原體IGG

JL-FA-149

Mycoplasma IgM

支原體IGM

JL-FA-150

Mycoplasma PCR

支原體PCR

JL-FA-151

Normal Human Plasma

正常人血漿

JL-FA-152

Normal Human Serum

正常人血清

JL-FA-153

Nuclear Antibody Centromere

核抗體著絲粒

JL-FA-154

Nuclear Antibody, Speckled ANA

核抗體,斑點抗核抗體

JL-FA-155

Nuclear Antibody, Nucleolar ANA

核抗體,核仁抗核抗體

JL-FA-156

Nuclear Antibody, Homogeneous ANA

核抗體,同質(zhì)抗核抗體

JL-FA-157

Nuclear Antiobody, Speckled. (ANA) Negative

核抗體,斑點。抗核抗體陰性

JL-FA-158

P-ANCA (associated neutrophil cytoplasmic antibodies)

相關(guān)的嗜中性粒細胞胞漿抗體

JL-FA-159

Parietal Cell Antibody (PCA)

胃)壁細胞抗體

JL-FA-160

Parvo positive plasma

細小病毒陽性血漿

JL-FA-161

Parvo IgM

細小病毒 IGM

JL-FA-162

Parvo IgG

細小病毒 IGG

JL-FA-163

Parvo Negative Plasma

細小病毒陰性血漿

JL-FA-164

Parvo DNA positive

細小病毒 DNA 陽性

JL-FA-165

Phospholipid Positive Plasma

磷脂陽性血漿

JL-FA-166

Prothrombin

凝血酶原,凝血因子

JL-FA-167

Rheumatoid Factor (RF) <1000 IU/mL

類風濕因子<1000 IU/mL

JL-FA-168

Rheumatoid Factor (RF) 1001-2000 IU/mL

類風濕因子1001-2000 IU/mL

JL-FA-169

Rheumatoid Factor (RF) 2001-4000 IU/mL

類風濕因子 2001-4000 IU/mL

JL-FA-170

Rheumatoid Factor (RF) 4001-5000 IU/mL

類風濕因子 4001-5000 IU/mL

JL-FA-171

Rheumatoid Factor (RF) >5000 IU/mL

類風濕因子>5000 IU/mL

JL-FA-172

Ribonucleoprotein (RNP) Positive

核糖核蛋白陽性

JL-FA-173

Rubella Chimeric

風疹

JL-FA-174

Rubella Negative

風疹陰性

JL-FA-175

Rubella IgG

風疹I(lǐng)GG

JL-FA-176

Rubella IgM

風疹I(lǐng)GM

JL-FA-177

Rubeola Negative Plasma

風疹陰性血漿

JL-FA-178

Rubeola IgG

風疹I(lǐng)GG

JL-FA-179

Scleroderma (Scl-70) Pos

膠原沉著病,硬皮病,硬皮癥 陽性

JL-FA-180

Scleroderma (Scl-70) Negative

硬皮病陰性

JL-FA-181

Sickle Cell Fresh Whole Blood

鐮刀形紅細胞新鮮全血

JL-FA-182

Smith (SM)

抗Smith抗體陽性血清(SLE的特征性抗體)

JL-FA-183

SMITH RNP

抗RNP抗體陽性血清(SLE的特征性抗體)

JL-FA-184

Smooth Muscle (ASMA)

抗平滑肌抗體陽性血清

JL-FA-185

Sjogren syndrome antigen A (SSA) Positive

舍格倫綜合征或干燥綜合征抗原A 陽性

JL-FA-186

Sjogren syndrome antigen B (SSB) Positive

舍格倫綜合征抗原B 陽性

JL-FA-187

Sjogren syndrome antigen B (SSB) Negative

舍格倫綜合征抗原B陰性

JL-FA-188

Streptolysin O Ab (ASO)

鏈球菌溶血素O抗體

JL-FA-189

Syphilis (RPR - Rapid Plasma Reagin) Positive Plasma

梅毒(梅毒-快速血漿反應)陽性血漿

JL-FA-190

Syphilis (RPR - Rapid Plasma Reagin) Negative Plasma

梅毒(梅毒-快速血漿反應)陰性血漿

JL-FA-191

Syphilis/ATA/T. pallidum IgG

梅毒ATA/T,蒼白球IGG

JL-FA-192

Syphilis/ATA/T. pallidum IgM

梅毒ATA/T,蒼白球IGM

JL-FA-193

Systemic Lupus Erythematosus (SLE) Positive

全身性紅斑狼瘡陽性

JL-FA-194

Systemic Lupus Erythematosus (SLE) Negative

全身性紅斑狼瘡陰性

JL-FA-195

TG/TPO Positive (Standard Titer 1,000 - 3000 IU/mL)

甲狀腺球蛋白/甲狀腺過氧化物酶陽性

JL-FA-196

TG/TPO Negative

甲狀腺球蛋白/甲狀腺過氧化物酶陰性

JL-FA-197

TTG (Tissue Transglutaminase)

組織轉(zhuǎn)谷氨酰胺酶

JL-FA-198

TTG (Tissue Transglutaminase) IgA

組織轉(zhuǎn)谷氨酰胺酶 IGA

JL-FA-199

ToRCH (Toxo, Rubella, CMV, HSV) Positive

優(yōu)生優(yōu)育(弓形蟲,風疹,巨細胞,單胞)陽性

JL-FA-200

ToRCH (Toxo, Rubella, CMV, HSV) Negative

優(yōu)生優(yōu)育(弓形蟲,風疹,巨細胞,單胞)陰性

JL-FA-201

Toxoplasmosis (Toxo)

弓形蟲病

JL-FA-202

Toxoplasmosis (Toxo) IgG

弓形蟲病IGG

JL-FA-203

Toxoplasmosis (Toxo) IgM

弓形蟲病IGM

JL-FA-204

Thyroglobulin (TG) Positive Plasma

甲狀腺球蛋白陽性血漿

JL-FA-205

Thyroglobulin (TG) Negative

甲狀腺球蛋白陰性

JL-FA-206

Varicella-Zoster Virus (VZV) Negative

水痘-帶狀皰疹病毒陰性

JL-FA-207

Varicella-Zoster Virus (VZV) IgG

水痘-帶狀皰疹病毒IGG

JL-FA-208

Varicella-Zoster Virus (VZV) IgM

水痘-帶狀皰疹病毒IGM

JL-FA-209

West Nile Virus (WNV)

西尼羅河腦炎病毒

JL-FA-210

West Nile Virus (WNV) IgM

西尼羅河腦炎病毒IGM

美國

在小鼠中進行的這項研究也顯示腎臟自我更新的能力。不是單一型的腎干細胞就可替換任何丟失或受損的腎臟組織,而是駐留在腎臟的不同部分稍微??更專門的干細胞產(chǎn)生每個類型的腎組織??內(nèi)的新細胞。
“這就像有分支的樹,其中每個分支考慮其自身的成長,而不是依賴于軀干的照顧,”德克爾說。
科學家還發(fā)現(xiàn),這些細胞是通過一個名為Wnt蛋白的細胞通路的活化作出生長的決定。Rinkevich說,即使腎上皮細胞的數(shù)量看起來一樣,zui健壯腎臟形成能力可追溯到前體細胞中的Wnt信號被激活,并且只能生長為某些特定類型的腎組織。“這提示了Wnt信號是負責新腎組織的成長提供了一個治療目標,以通過促進或恢復腎臟的再生能力,”他說。“我們也許能夠打開Wnt信號通路產(chǎn)生新的腎臟形成細胞。”
研究人員說,這項研究發(fā)現(xiàn)對于科學家試圖在實驗室創(chuàng)造腎部分有著至關(guān)重要的影響。
然而,他們警告說,這樣的進步并不迫在眉睫。“為了在實驗室里長出整個腎臟是復雜的,因為我們需要協(xié)調(diào)許多不同種類的前體細胞的活性,” 德克爾說。“這不象血液和免疫系統(tǒng)可以從一種類型的干細胞再生。”
奧地利科學技術(shù)研究所(IST)的副教授Harald Janovjak,與維也納醫(yī)學大學癌癥研究學會的副教授邁克爾·格呂施,一起利用光“遙控”癌細胞的行為,相關(guān)文章發(fā)表于本周的EMBO雜志上。這項工作*將光遺傳學應用到癌癥研究的新領(lǐng)域。
為了解細胞信號的動態(tài),研究人員需要將膜受體蛋白激活和使其失活,膜受體蛋白作為一個細胞內(nèi)外世界之間的中轉(zhuǎn)站。理想情況下,這種激活在短時間(幾秒到幾分鐘)以及近的目標位置(微米到毫米)內(nèi)發(fā)生。然而,如此高水平的活化精密度不能使用當前的藥理學和遺傳學的方法來實現(xiàn)。光遺傳學利用光來控制細胞的活性,以及具有在時間和空間上精確地被應用和移動(施加和除去)的優(yōu)點。Janovjak,格呂施和同事重新設(shè)計受體酪氨酸激酶(RTKs),在光的控制下,感測生長因子和激素的必要的細胞表面受體。
當一個信號分子結(jié)合到細胞表面的RTKs,兩種受體相互結(jié)合的過程稱為二聚化作用。這個過程會激活細胞的信號轉(zhuǎn)導。Janovjak,格呂施和同事將哺乳動物的RTKs的那些部分與光 - 氧 - 電壓傳感領(lǐng)域(鑒定黃綠藻的可逆光傳感器)結(jié)合。在工程化受體中,二聚化步驟和隨后的細胞信號轉(zhuǎn)導現(xiàn)在可以通過光隨著藻蛋白光感打開和關(guān)閉,以及彼此結(jié)合。在腫瘤細胞中,工程受體的活化導致細胞形態(tài)變化,細胞增殖和基因表達,增加癌癥的惡性程度的特性。在血細胞中,活化導致細胞出芽,典型的新血管形成。

美國

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This study, conducted in mice, also shows the kidney's ability to self-renew. Rather than a single type of kidney stem cell that replaces any lost or damaged kidney tissue, it resides in a slightly more specialized, more specialized stem cell that produces new cells within each type of kidney tissue.
"It's like a tree with branches, each of which takes into account its own growth, not its torso care," Decker said.
Scientists also found that these cells are the decision to grow through the activation of a cellular pathway called Wnt protein. Rinkevich said that even though the number of renal epithelial cells looks the same, the most robust kidney formation can be traced back to the activation of Wnt signaling in precursor cells and can only grow to certain types of kidney tissue. "This suggests that Wnt signaling is responsible for the growth of new kidney tissue and provides a therapeutic target to promote or restore the regenerative capacity of the kidneys," he said. "We may be able to turn on the Wnt signaling pathway to produce new kidney-forming cells."
The researchers said the study found a crucial impact on scientists trying to create parts of the kidney in the lab.
However, they warned that such progress is not imminent. "To grow an entire kidney in a lab is complicated because we need to coordinate the activity of many different kinds of precursor cells," Decker said. "It's not like the blood and the immune system can regenerate from one type of stem cell."
Harald Janovjak, an associate professor at the Austrian Institute of Science and Technology (IST), and Michael Gruissch, associate professor at the Society for Cancer Research at the Medical University of Vienna, use light to "control" cancer cells in an article published this week in the EMBO journal. This work, for the first time, applies optogenetics to new areas of cancer research.
To understand the dynamics of cell signaling, researchers need to activate and inactivate membrane receptor proteins, which act as a transit site between the cell's inner and outer cells. Ideally, this activation occurs within short periods of time (seconds to minutes) and near target locations (micrometers to millimeters). However, such a high level of activation precision can not be achieved using current pharmacological and genetic approaches. Photogenetics uses light to control the activity of cells, and has the advantage of being precisely applied and moved (applied and removed) in time and space. Janovjak, Gruch and colleagues redesigned their receptor tyrosine kinases (RTKs) to sense the necessary cell surface receptors for growth factors and hormones under the control of light.
When a signaling molecule binds to a cell surface RTKs, the two receptors bind to each other as a dimerization. This process activates cell signaling. Janovjak, Gruch and colleagues combined those parts of the mammalian RTKs with the field of photo-oxygen-voltage sensing, a reversible light sensor that identifies Chlorella. In engineered receptors, the dimerization step and subsequent cellular signal transduction can now be turned on and off by light along with the algin protein and bind to each other. In tumor cells, activation of engineered receptors leads to changes in cell morphology, cell proliferation and gene expression, and increases the malignancy of cancers. In blood cells, activation leads to cell budding, typical neovascularization.

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